Product Name: NMN Pen 

Formulation: 2.6 mL pre-filled pen 

Clicks per Pen: 240 

Total Amount: 1500 mg Nicotinamide Mononucleotide (NMN) 

Supplied with: 6 sterile needles (extras available) 

Description 

Nicotinamide Mononucleotide (NMN) is a nucleotide derived from ribose, nicotinamide, nicotinamide riboside, and niacin (vitamin B3). Its chemical structure is C,,H15N2OP, consisting of a nicotinamide moiety linked to a ribose sugar phosphorylated at the 5‘ position. NMN is the direct precursor to nicotinamide adenine dinucleotide (NAD), a critical coenzyme found in every cell. 

Mechanism of Action 

NMN is rapidly taken up by cells via the Slc12a8 transporter (in small intestine and other tissues) and converted to NAD* through the salvage pathway, primarily by nicotinamide mononucleotide adenylyl transferases (NMNAT1-3). Elevated NAD* levels activate key NAD+-dependent enzymes: 

• Sirtuins (SIRT1-7) epigenetic regulation, DNA repair, mitochondrial biogenesis, inflammation control, and longevity pathways 
• PARPS → DNA damage repair and genomic stability 
• CD38/CD157 → calcium signalling and immune modulation 

The net result is enhanced mitochondrial function, increased energy production (ATP), improved metabolic flexibility, reduced oxidative stress, better insulin sensitivity, and activation of cellular repair and anti aging mechanisms. 

Indications & Usage 

NMN is used to support cellular energy metabolism, mitochondrial health, and age–related physiological processes. It is indicated for: 

• Promotion of NAD+ levels and cellular energy production 
• Support for mitochondrial function, metabolic efficiency, and insulin sensitivity
• Assistance during age-related decline in vitality, endurance, and recovery capacity 
• General support for healthy aging, cognitive resilience, and physical performance 

Contraindications & Warnings 

Do not use if you have: 

• Known hypersensitivity to NMN or any excipient 
• Active malignancy (theoretical concern regarding enhanced cellular metabolism) Severe uncontrolled liver or kidney disease 
• Pregnancy or breastfeeding 
• Age under 18 years 

Warnings 

• Use only under medical supervision with periodic monitoring (liver function, glucose metabolism, and clinical parameters). 
• Not a substitute for lifestyle interventions or approved therapies for metabolic or age–related conditions. 
• High doses may cause transient flushing or gastrointestinal discomfort. 
• Discontinue immediately and seek medical attention if severe symptoms occur (e.g., severe abdominal pain, allergic reaction, or unexpected neurological changes). 

Dosage & Administration 

• Subcutaneous injection only. 
• Daily Wellness / Longevity: 3-4 clicks daily in the morning (18.75-25 mg NMN)
• Therapeutic/Mitochondrial Support: 8-12 clicks daily, 5x per week (50-75 mg NMN) 
• High Performance / Anti-Aging Protocol: 20 clicks (125 mg NMN) three times per week for 4-6 weeks 
• Frequency: As per protocol (daily for wellness/therapeutic; 3x/week for high performance)
• Timing: Morning (preferred for energy and NAD* support) or as directed by your healthcare provider 

Administration Instructions

1. Wash hands and prepare a clean surface. 
2. Attach a sterile needle. 
3. Dial the required number of clicks. 
4. Clean injection site (abdomen or thigh) with alcohol swab. 
5. Insert needle at 45-90° angle and inject slowly. 
6. Withdraw needle, dispose safely, and cap the pen. 
7. Rotate injection sites to minimize irritation. 
8. Always inspect solution before use: Do not inject if cloudy, discoloured, or containing particles. 

Side Effects 

NMN is generally well tolerated across studied doses. Reported reactions are uncommon and usually mild/transient, including: 

• Mild injection–site irritation, redness, or itching 
• Transient headache, light-headedness, or flushing 
• Temporary gastrointestinal discomfort (nausea, bloating) 
• Rare fatigue or changes in energy levels during initial use 
• If any severe or persistent symptoms occur (e.g., severe headache, abdominal pain, or allergic signs), discontinue use and contact your healthcare provider immediately. 

Storage & Handling 

• Store either in refrigerator (fridge); never freeze or in a cool dry place (≤25-30°C / 77-86°F). Keep pen capped and protected from light and heat. 
• After first use: Same storage conditions. 
• Keep out of reach of children. 
• Discard if expired or solution appears abnormal. 

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IMPORTANT NOTICE 

This product is not intended to diagnose, treat, cure, or prevent any disease. Statements have not been evaluated by the FDA, SAHPRA, or other authorities. Always consult a licensed healthcare provider before use, especially if pregnant, breastfeeding, under 18, or managing medical conditions.